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Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism

Ribosome assembly is an essential process that is linked to human congenital diseases and tumorigenesis. While great progress has been made in deciphering mechanisms governing ribosome biogenesis in eukaryotes, an inventory of factors that support ribosome synthesis in human cells is still missing,...

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Detalles Bibliográficos
Autores principales:	Dörner, Kerstin, Badertscher, Lukas, Horváth, Bianka, Hollandi, Réka, Molnár, Csaba, Fuhrer, Tobias, Meier, Roger, Sárazová, Marie, van den Heuvel, Jasmin, Zamboni, Nicola, Horvath, Peter, Kutay, Ulrike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934630/ https://www.ncbi.nlm.nih.gov/pubmed/35150276 http://dx.doi.org/10.1093/nar/gkac072

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