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Drop-off-reinitiation triggered by EF-G-driven mistranslocation and its alleviation by EF-P

In ribosomal translation, peptidyl transfer occurs between P-site peptidyl-tRNA and A-site aminoacyl-tRNA, followed by translocation of the resulting P-site deacylated-tRNA and A-site peptidyl-tRNA to E and P site, respectively, mediated by EF-G. Here, we report that mistranslocation of P-site pepti...

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Detalles Bibliográficos
Autores principales: Tajima, Kenya, Katoh, Takayuki, Suga, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934632/
https://www.ncbi.nlm.nih.gov/pubmed/35188576
http://dx.doi.org/10.1093/nar/gkac068