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Drop-off-reinitiation triggered by EF-G-driven mistranslocation and its alleviation by EF-P
In ribosomal translation, peptidyl transfer occurs between P-site peptidyl-tRNA and A-site aminoacyl-tRNA, followed by translocation of the resulting P-site deacylated-tRNA and A-site peptidyl-tRNA to E and P site, respectively, mediated by EF-G. Here, we report that mistranslocation of P-site pepti...
Autores principales: | Tajima, Kenya, Katoh, Takayuki, Suga, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934632/ https://www.ncbi.nlm.nih.gov/pubmed/35188576 http://dx.doi.org/10.1093/nar/gkac068 |
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