Non-equilibrium structural dynamics of supercoiled DNA plasmids exhibits asymmetrical relaxation

Many cellular processes occur out of equilibrium. This includes site-specific unwinding in supercoiled DNA, which may play an important role in gene regulation. Here, we use the Convex Lens-induced Confinement (CLiC) single-molecule microscopy platform to study these processes with high-throughput a...

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Detalles Bibliográficos
Autores principales: Shaheen, Cynthia, Hastie, Cameron, Metera, Kimberly, Scott, Shane, Zhang, Zhi, Chen, Sitong, Gu, Gracia, Weber, Lisa, Munsky, Brian, Kouzine, Fedor, Levens, David, Benham, Craig, Leslie, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934633/
https://www.ncbi.nlm.nih.gov/pubmed/35188541
http://dx.doi.org/10.1093/nar/gkac101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934633/
https://www.ncbi.nlm.nih.gov/pubmed/35188541
http://dx.doi.org/10.1093/nar/gkac101

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