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The interplay of supercoiling and thymine dimers in DNA
Thymine dimers are a major mutagenic photoproduct induced by UV radiation. While they have been the subject of extensive theoretical and experimental investigations, questions of how DNA supercoiling affects local defect properties, or, conversely, how the presence of such defects changes global sup...
Autores principales: | Lim, Wilber, Randisi, Ferdinando, Doye, Jonathan P K, Louis, Ard A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934635/ https://www.ncbi.nlm.nih.gov/pubmed/35188542 http://dx.doi.org/10.1093/nar/gkac082 |
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