H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeler function

The Isw1b chromatin-remodeling complex is specifically recruited to gene bodies to help retain pre-existing histones during transcription by RNA polymerase II. Recruitment is dependent on H3K36 methylation and the Isw1b subunit Ioc4, which contains an N-terminal PWWP domain. Here, we present the cry...

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Detalles Bibliográficos
Autores principales: Li, Jian, Bergmann, Lena, Rafael de Almeida, Andreia, Webb, Kimberly M, Gogol, Madelaine M, Voigt, Philipp, Liu, Yingfang, Liang, Huanhuan, Smolle, Michaela M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934638/
https://www.ncbi.nlm.nih.gov/pubmed/35188579
http://dx.doi.org/10.1093/nar/gkac077

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