Virus-specific editing identification approach reveals the landscape of A-to-I editing and its impacts on SARS-CoV-2 characteristics and evolution

Upon SARS-CoV-2 infection, viral intermediates specifically activate the IFN response through MDA5-mediated sensing and accordingly induce ADAR1 p150 expression, which might lead to viral A-to-I RNA editing. Here, we developed an RNA virus-specific editing identification pipeline, surveyed 7622 RNA-...

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Detalles Bibliográficos
Autores principales: Song, Yulong, He, Xiuju, Yang, Wenbing, Wu, Yaoxing, Cui, Jun, Tang, Tian, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Data Resources and Analyses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934641/
https://www.ncbi.nlm.nih.gov/pubmed/35234938
http://dx.doi.org/10.1093/nar/gkac120

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