The first crystal structures of hybrid and parallel four-tetrad intramolecular G-quadruplexes

G-quadruplexes (GQs) are non-canonical DNA structures composed of stacks of stabilized G-tetrads. GQs play an important role in a variety of biological processes and may form at telomeres and oncogene promoters among other genomic locations. Here, we investigate nine variants of telomeric DNA from T...

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Detalles Bibliográficos
Autores principales: Beseiso, Dana, Chen, Erin V, McCarthy, Sawyer E, Martin, Kailey N, Gallagher, Elizabeth P, Miao, Joanne, Yatsunyk, Liliya A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934647/
https://www.ncbi.nlm.nih.gov/pubmed/35212369
http://dx.doi.org/10.1093/nar/gkac091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934647/
https://www.ncbi.nlm.nih.gov/pubmed/35212369
http://dx.doi.org/10.1093/nar/gkac091

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