Cargando…

Does rapid sequence divergence preclude RNA structure conservation in vertebrates?

Accelerated evolution of any portion of the genome is of significant interest, potentially signaling positive selection of phenotypic traits and adaptation. Accelerated evolution remains understudied for structured RNAs, despite the fact that an RNA’s structure is often key to its function. RNA stru...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seemann, Stefan E, Mirza, Aashiq H, Bang-Berthelsen, Claus H, Garde, Christian, Christensen-Dalsgaard, Mikkel, Workman, Christopher T, Pociot, Flemming, Tommerup, Niels, Gorodkin, Jan, Ruzzo, Walter L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934657/ https://www.ncbi.nlm.nih.gov/pubmed/35188540 http://dx.doi.org/10.1093/nar/gkac067

Ejemplares similares

The identification and functional annotation of RNA structures conserved in vertebrates
por: Seemann, Stefan E., et al.
Publicado: (2017)

Transcriptomic landscape of lncRNAs in inflammatory bowel disease
por: Mirza, Aashiq H, et al.
Publicado: (2015)

Circulating MicroRNAs in Plasma of Hepatitis B e Antigen Positive Children Reveal Liver-Specific Target Genes
por: Winther, Thilde Nordmann, et al.
Publicado: (2014)

Cross-species high-resolution transcriptome profiling suggests biomarkers and therapeutic targets for ulcerative colitis
por: Yarani, Reza, et al.
Publicado: (2023)

Cell Type-Selective Expression of Circular RNAs in Human Pancreatic Islets
por: Kaur, Simranjeet, et al.
Publicado: (2018)

Long non-coding RNAs as novel players in β cell function and type 1 diabetes
por: Mirza, Aashiq H., et al.
Publicado: (2017)

The emerging role of lncRNAs in inflammatory bowel disease
por: Yarani, Reza, et al.
Publicado: (2018)

Effects of GWAS-Associated Genetic Variants on lncRNAs within IBD and T1D Candidate Loci
por: Mirza, Aashiq H., et al.
Publicado: (2014)

A Dual Systems Genetics Approach Identifies Common Genes, Networks, and Pathways for Type 1 and 2 Diabetes in Human Islets
por: Kaur, Simranjeet, et al.
Publicado: (2021)

Independent component and pathway-based analysis of miRNA-regulated gene expression in a model of type 1 diabetes
por: Bang-Berthelsen, Claus H, et al.
Publicado: (2011)

A splice-site variant in the lncRNA gene RP1-140A9.1 cosegregates in the large Volkmann cataract family
por: Eiberg, Hans, et al.
Publicado: (2019)

Associating transcription factors and conserved RNA structures with gene regulation in the human brain
por: Hecker, Nikolai, et al.
Publicado: (2017)

Differential Plasma MicroRNA Profiles in HBeAg Positive and HBeAg Negative Children with Chronic Hepatitis B
por: Winther, Thilde Nordmann, et al.
Publicado: (2013)

Hepatitis B Surface Antigen Quantity Positively Correlates with Plasma Levels of microRNAs Differentially Expressed in Immunological Phases of Chronic Hepatitis B in Children
por: Winther, Thilde Nordmann, et al.
Publicado: (2013)

Identification and characterization of novel conserved RNA structures in Drosophila
por: Kirsch, Rebecca, et al.
Publicado: (2018)

Optimizing RNA structures by sequence extensions using RNAcop
por: Hecker, Nikolai, et al.
Publicado: (2015)

Influence of Disease Duration on Circulating Levels of miRNAs in Children and Adolescents with New Onset Type 1 Diabetes
por: Samandari, Nasim, et al.
Publicado: (2018)

Transcripts with in silico predicted RNA structure are enriched everywhere in the mouse brain
por: Seemann, Stefan E, et al.
Publicado: (2012)

Sequence and expression analysis of gaps in human chromosome 20
por: Minocherhomji, Sheroy, et al.
Publicado: (2012)

Pro-Inflammatory Cytokines Promote the Transcription of Circular RNAs in Human Pancreatic β Cells
por: Kaur, Simranjeet, et al.
Publicado: (2022)

Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts
por: Kang, Wenjing, et al.
Publicado: (2017)

Precluding rare outcomes by predicting their absence
por: Schoon, Eric W., et al.
Publicado: (2019)

Conservation and divergence of protein pathways in the vertebrate heart
por: Federspiel, Joel D., et al.
Publicado: (2019)

Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression
por: Bergholdt, Regine, et al.
Publicado: (2012)

Breast Milk-Derived Extracellular Vesicles Enriched in Exosomes From Mothers With Type 1 Diabetes Contain Aberrant Levels of microRNAs
por: Mirza, Aashiq H., et al.
Publicado: (2019)

A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells
por: Vestergaard, Anna Lindeløv, et al.
Publicado: (2016)

Practical problems may preclude realization of this proposal
por: Della Mea, Vincenzo
Publicado: (2000)

Unilateral Diaphragmatic Agenesis Precluding Laparoscopic Cholecystectomy
por: Wakai, Abel, et al.
Publicado: (2000)

Explaining Underrepresentation: A Theory of Precluded Interest
por: Cheryan, Sapna, et al.
Publicado: (2010)

Circulating Levels of MicroRNA from Children with Newly Diagnosed Type 1 Diabetes and Healthy Controls: Evidence That miR-25 Associates to Residual Beta-Cell Function and Glycaemic Control during Disease Progression
por: Nielsen, Lotte B., et al.
Publicado: (2012)

Erratum to “Circulating Levels of MicroRNA from Children with Newly Diagnosed Type 1 Diabetes and Healthy Controls: Evidence That miR-25 Associates to Residual Beta-Cell Function and Glycaemic Control during Disease Progression”
por: Nielsen, Lotte B., et al.
Publicado: (2012)

Conserved and Divergent Patterns of DNA Methylation in Higher Vertebrates
por: Jiang, Ning, et al.
Publicado: (2014)

Functionally conserved enhancers with divergent sequences in distant vertebrates
por: Yang, Song, et al.
Publicado: (2015)

Differentially Expressed miRNAs in Ulcerative Colitis and Crohn’s Disease
por: Yarani, Reza, et al.
Publicado: (2022)

Cortical Gamma Oscillations: Details of Their Genesis Preclude a Role in Cognition
por: Merker, Bjorn H.
Publicado: (2016)

Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?
por: Egefjord, Lærke, et al.
Publicado: (2009)

The neglected sun: why the sun precludes climate catastrophe
por: Vahrenholt, Fritz, et al.
Publicado: (2012)

Atrio‐Hisian block precludes preexcitation—What is the mechanism?
por: Prabhu, Mukund Aravind, et al.
Publicado: (2018)

Plasma Exosome-Enriched Extracellular Vesicles From Lactating Mothers With Type 1 Diabetes Contain Aberrant Levels of miRNAs During the Postpartum Period
por: Frørup, Caroline, et al.
Publicado: (2021)

Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs
por: Laurent, Jon M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2b1e0iuhrrqoojgsn9ena6o44j