SLX4 dampens MutSα-dependent mismatch repair

The tumour suppressor SLX4 plays multiple roles in the maintenance of genome stability, acting as a scaffold for structure-specific endonucleases and other DNA repair proteins. It directly interacts with the mismatch repair (MMR) protein MSH2 but the significance of this interaction remained unknown...

Descripción completa

Detalles Bibliográficos
Autores principales: Guervilly, Jean-Hugues, Blin, Marion, Laureti, Luisa, Baudelet, Emilie, Audebert, Stéphane, Gaillard, Pierre-Henri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934664/
https://www.ncbi.nlm.nih.gov/pubmed/35166826
http://dx.doi.org/10.1093/nar/gkac075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934664/
https://www.ncbi.nlm.nih.gov/pubmed/35166826
http://dx.doi.org/10.1093/nar/gkac075

Ejemplares similares