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SLX4 dampens MutSα-dependent mismatch repair

The tumour suppressor SLX4 plays multiple roles in the maintenance of genome stability, acting as a scaffold for structure-specific endonucleases and other DNA repair proteins. It directly interacts with the mismatch repair (MMR) protein MSH2 but the significance of this interaction remained unknown...

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Detalles Bibliográficos
Autores principales:	Guervilly, Jean-Hugues, Blin, Marion, Laureti, Luisa, Baudelet, Emilie, Audebert, Stéphane, Gaillard, Pierre-Henri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934664/ https://www.ncbi.nlm.nih.gov/pubmed/35166826 http://dx.doi.org/10.1093/nar/gkac075

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