Aorta in Pathologies May Function as an Immune Organ by Upregulating Secretomes for Immune and Vascular Cell Activation, Differentiation and Trans-Differentiation—Early Secretomes may Serve as Drivers for Trained Immunity

To determine whether aorta becomes immune organ in pathologies, we performed transcriptomic analyses of six types of secretomic genes (SGs) in aorta and vascular cells and made the following findings: 1) 53.7% out of 21,306 human protein genes are classified into six secretomes, namely, canonical, c...

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Detalles Bibliográficos
Autores principales: Lu, Yifan, Sun, Yu, Xu, Keman, Saaoud, Fatma, Shao, Ying, Drummer, Charles, Wu, Sheng, Hu, Wenhui, Yu, Jun, Kunapuli, Satya P., Bethea, John R., Vazquez-Padron, Roberto I., Sun, Jianxin, Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934864/
https://www.ncbi.nlm.nih.gov/pubmed/35320939
http://dx.doi.org/10.3389/fimmu.2022.858256

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