Myocarditis following rAd26 and rAd5 vector‐based COVID‐19 vaccine: case report

SARS‐CoV‐2 vaccines provide a safe solution with a major impact on reducing the spread of the virus and mild side effects. Research has shown rare cases of myocarditis after mRNA vaccines. This study presents a 29‐year‐old male with chest pain after 48 h of receiving rAd26 and rAd5 vector‐based COVI...

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Autores principales: Naghashzadeh, Farah, Shafaghi, Shadi, Dorudinia, Atosa, Naji, Seyed Alireza, Marjani, Majid, Amin, Ahmad, Mohamadifar, Arezoo, Noorali, Sima, Kashani, Babak Sharif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934948/
https://www.ncbi.nlm.nih.gov/pubmed/35106967
http://dx.doi.org/10.1002/ehf2.13821
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author Naghashzadeh, Farah
Shafaghi, Shadi
Dorudinia, Atosa
Naji, Seyed Alireza
Marjani, Majid
Amin, Ahmad
Mohamadifar, Arezoo
Noorali, Sima
Kashani, Babak Sharif
author_facet Naghashzadeh, Farah
Shafaghi, Shadi
Dorudinia, Atosa
Naji, Seyed Alireza
Marjani, Majid
Amin, Ahmad
Mohamadifar, Arezoo
Noorali, Sima
Kashani, Babak Sharif
author_sort Naghashzadeh, Farah
collection PubMed
description SARS‐CoV‐2 vaccines provide a safe solution with a major impact on reducing the spread of the virus and mild side effects. Research has shown rare cases of myocarditis after mRNA vaccines. This study presents a 29‐year‐old male with chest pain after 48 h of receiving rAd26 and rAd5 vector‐based COVID‐19 vaccine (Sputnik V vaccine). The electrocardiogram revealed ST‐segment elevation. Also, the laboratory screening was remarkable for elevated cardiac Troponin‐I level, and leukocytosis; and echocardiography depicted severe left ventricular systolic dysfunction. Overall, endomyocardial biopsy proved lymphocytic myocarditis such that the patient was successfully treated with immunosuppressive and guideline‐directed medical treatment.
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spelling pubmed-89349482022-03-24 Myocarditis following rAd26 and rAd5 vector‐based COVID‐19 vaccine: case report Naghashzadeh, Farah Shafaghi, Shadi Dorudinia, Atosa Naji, Seyed Alireza Marjani, Majid Amin, Ahmad Mohamadifar, Arezoo Noorali, Sima Kashani, Babak Sharif ESC Heart Fail Case Reports SARS‐CoV‐2 vaccines provide a safe solution with a major impact on reducing the spread of the virus and mild side effects. Research has shown rare cases of myocarditis after mRNA vaccines. This study presents a 29‐year‐old male with chest pain after 48 h of receiving rAd26 and rAd5 vector‐based COVID‐19 vaccine (Sputnik V vaccine). The electrocardiogram revealed ST‐segment elevation. Also, the laboratory screening was remarkable for elevated cardiac Troponin‐I level, and leukocytosis; and echocardiography depicted severe left ventricular systolic dysfunction. Overall, endomyocardial biopsy proved lymphocytic myocarditis such that the patient was successfully treated with immunosuppressive and guideline‐directed medical treatment. John Wiley and Sons Inc. 2022-02-01 /pmc/articles/PMC8934948/ /pubmed/35106967 http://dx.doi.org/10.1002/ehf2.13821 Text en © 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Naghashzadeh, Farah
Shafaghi, Shadi
Dorudinia, Atosa
Naji, Seyed Alireza
Marjani, Majid
Amin, Ahmad
Mohamadifar, Arezoo
Noorali, Sima
Kashani, Babak Sharif
Myocarditis following rAd26 and rAd5 vector‐based COVID‐19 vaccine: case report
title Myocarditis following rAd26 and rAd5 vector‐based COVID‐19 vaccine: case report
title_full Myocarditis following rAd26 and rAd5 vector‐based COVID‐19 vaccine: case report
title_fullStr Myocarditis following rAd26 and rAd5 vector‐based COVID‐19 vaccine: case report
title_full_unstemmed Myocarditis following rAd26 and rAd5 vector‐based COVID‐19 vaccine: case report
title_short Myocarditis following rAd26 and rAd5 vector‐based COVID‐19 vaccine: case report
title_sort myocarditis following rad26 and rad5 vector‐based covid‐19 vaccine: case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934948/
https://www.ncbi.nlm.nih.gov/pubmed/35106967
http://dx.doi.org/10.1002/ehf2.13821
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