Urolithin A protects against acetaminophen-induced liver injury in mice via sustained activation of Nrf2

Acetaminophen overdose is a leading cause of acute live failure worldwide. N-acetylcysteine (NAC), as the only antidote, is limited due to its narrow therapeutic time window. Here we demonstrated that Urolithin A (UA), a metabolite of ellagitannin natural products in the gastrointestinal flora, prot...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Zhimin, Yi, Wei, Tang, Junyuan, Sun, Yuling, Huang, Jianrong, Lan, Tian, Dai, Xiaoyan, Xu, Suowen, Jin, Zheng-Gen, Wu, Xiaoqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935220/
https://www.ncbi.nlm.nih.gov/pubmed/35342347
http://dx.doi.org/10.7150/ijbs.69116

Ejemplares similares

Ejemplares similares