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Dissection of Targeting Molecular Mechanisms of Aristolochic Acid-induced Nephrotoxicity via a Combined Deconvolution Strategy of Chemoproteomics and Metabolomics

Aristolochic acid (AA), mainly derived from herbal Aristolochia and Asarum plants, was listed as a human carcinogen class I in 2002. Aristolochic acid nephropathy (AAN) is a rapidly progressive tubulointerstitial nephritis and urothelial cancer caused by AA. However, the targeting molecular mechanis...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Luo, Piao, Chen, Jiayun, Yang, Chuanbin, Xia, Fei, Zhang, Junzhe, Tang, Huan, Liu, Dandan, Gu, Liwei, Shi, Qiaoli, He, Xueling, Yang, Tong, Wang, Jigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935225/
https://www.ncbi.nlm.nih.gov/pubmed/35342337
http://dx.doi.org/10.7150/ijbs.69618