Cargando…
Dissection of Targeting Molecular Mechanisms of Aristolochic Acid-induced Nephrotoxicity via a Combined Deconvolution Strategy of Chemoproteomics and Metabolomics
Aristolochic acid (AA), mainly derived from herbal Aristolochia and Asarum plants, was listed as a human carcinogen class I in 2002. Aristolochic acid nephropathy (AAN) is a rapidly progressive tubulointerstitial nephritis and urothelial cancer caused by AA. However, the targeting molecular mechanis...
Autores principales: | Zhang, Qian, Luo, Piao, Chen, Jiayun, Yang, Chuanbin, Xia, Fei, Zhang, Junzhe, Tang, Huan, Liu, Dandan, Gu, Liwei, Shi, Qiaoli, He, Xueling, Yang, Tong, Wang, Jigang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935225/ https://www.ncbi.nlm.nih.gov/pubmed/35342337 http://dx.doi.org/10.7150/ijbs.69618 |
Ejemplares similares
-
Dissection of cellular and molecular mechanisms of aristolochic acid-induced hepatotoxicity via single-cell transcriptomics
por: Luo, Piao, et al.
Publicado: (2022) -
Integrated single-cell transcriptomics and proteomics reveal cellular-specific responses and microenvironment remodeling in aristolochic acid nephropathy
por: Chen, Jiayun, et al.
Publicado: (2022) -
18beta-glycyrrhetinic acid induces ROS-mediated apoptosis to ameliorate hepatic fibrosis by targeting PRDX1/2 in activated HSCs
por: Zhang, Qian, et al.
Publicado: (2022) -
Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid
por: Lechner, Severin, et al.
Publicado: (2023) -
Systematic Overview of Aristolochic Acids: Nephrotoxicity, Carcinogenicity, and Underlying Mechanisms
por: Han, Jiayin, et al.
Publicado: (2019)