Cargando…

The RNF26/CBX7 axis modulates the TNF pathway to promote cell proliferation and regulate sensitivity to TKIs in ccRCC

Clear cell renal cell carcinoma (ccRCC) accounts for 85% of all malignant renal tumors. Currently, the pathogenesis of ccRCC is not fully understood. Chromobox (CBX) family proteins are the major subunits of PcG complexes and are implicated in regulating mammalian development. The CBX family consist...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Wentao, Wang, Haohui, Jian, Chengzhu, Li, Wei, Ye, Kun, Ren, Jiannan, Zhu, Liang, Wang, Yinhuai, Jin, Xin, Yi, Lu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935234/ https://www.ncbi.nlm.nih.gov/pubmed/35342353 http://dx.doi.org/10.7150/ijbs.69325

Ejemplares similares

OTUD1 stabilizes PTEN to inhibit the PI3K/AKT and TNF-alpha/NF-kappaB signaling pathways and sensitize ccRCC to TKIs
por: Liu, Wentao, et al.
Publicado: (2022)

Untangling ccRCC prognosis with SLINKY
por: Reinfeld, Bradley I., et al.
Publicado: (2017)

Functional and translational consequences of immunometabolic coevolution in ccRCC
por: Reznik, Ed, et al.
Publicado: (2023)

CD44 Is Associated with Poor Prognosis of ccRCC and Facilitates ccRCC Cell Migration and Invasion through HAS1/MMP9
por: Du, Tan, et al.
Publicado: (2023)

Pivotal biomarker expression and drug screening in advanced ccRCC
por: Xiao, Wen, et al.
Publicado: (2020)

SDHB Suppresses the Tumorigenesis and Development of ccRCC by Inhibiting Glycolysis
por: Fang, Zhiyu, et al.
Publicado: (2021)

Identification of key genes of the ccRCC subtype with poor prognosis
por: Puzanov, Grigory Andreevich
Publicado: (2022)

MT1X is an oncogene and indicates prognosis in ccRCC
por: Ding, Yanpeng, et al.
Publicado: (2022)

Cuproptosis in ccRCC: key player in therapeutic and prognostic targets
por: Lv, Yang, et al.
Publicado: (2023)

Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC
por: Xue, Wei, et al.
Publicado: (2023)

Thioredoxin 1 (Trx1) is associated with poor prognosis in clear cell renal cell carcinoma (ccRCC): an example for the crucial role of redox signaling in ccRCC
por: Ribback, Silvia, et al.
Publicado: (2021)

Does the Urinary Proteome Reflect ccRCC Stage and Grade Progression?
por: Santorelli, Lucia, et al.
Publicado: (2021)

A multiomics disease progression signature of low-risk ccRCC
por: Strauss, Philipp, et al.
Publicado: (2022)

Bioinformatics Analysis of Prognostic Value of SPC24 in ccRCC and Pan-Cancer
por: Zhang, Jipeng, et al.
Publicado: (2022)

Identification of FDFT1 as a potential biomarker associated with ferroptosis in ccRCC
por: Huang, Ruizhen, et al.
Publicado: (2022)

YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway
por: Li, Wei, et al.
Publicado: (2022)

Identification of AKI signatures and classification patterns in ccRCC based on machine learning
por: Wang, Li, et al.
Publicado: (2023)

Identification of genes of prognostic value in the ccRCC microenvironment from TCGA database
por: Wan, Bangbei, et al.
Publicado: (2020)

Transcription Factor and miRNA Interplays Can Manifest the Survival of ccRCC Patients
por: Qin, Shijie, et al.
Publicado: (2019)

LRG1 May Accelerate the Progression of ccRCC via the TGF-β Pathway
por: Hong, Quan, et al.
Publicado: (2020)

CD146 as a Prognostic-Related Biomarker in ccRCC Correlating With Immune Infiltrates
por: Lv, Zheng, et al.
Publicado: (2021)

Overexpression CPT1A reduces lipid accumulation via PPARα/CD36 axis to suppress the cell proliferation in ccRCC: CPT1A inhibits ccRCC cell proliferation via PPARα/CD36 axis
por: Yang, Hui, et al.
Publicado: (2021)

SCD5 Regulation by VHL Affects Cell Proliferation and Lipid Homeostasis in ccRCC
por: Ganner, Athina, et al.
Publicado: (2023)

Expression of micro-RNAs and genes related to angiogenesis in ccRCC and associations with tumor characteristics
por: Oliveira, Rita de Cássia, et al.
Publicado: (2017)

In-Depth Mapping of the Urinary N-Glycoproteome: Distinct Signatures of ccRCC-related Progression
por: Santorelli, Lucia, et al.
Publicado: (2020)

PRR11 promotes ccRCC tumorigenesis by regulating E2F1 stability
por: Chen, Siming, et al.
Publicado: (2021)

A novel thinking: DDR axis refines the classification of ccRCC with distinctive prognosis, multi omics landscape and management strategy
por: Jiang, Aimin, et al.
Publicado: (2022)

Identification and validation of SERPINE1 as a prognostic and immunological biomarker in pan-cancer and in ccRCC
por: Li, Lingqin, et al.
Publicado: (2023)

PLK4 Is a Potential Biomarker for Abnormal Tumor Proliferation, Immune Infiltration, and Prognosis in ccRCC
por: Hu, Chenglu, et al.
Publicado: (2022)

Expression of pre-selected TMEMs with predicted ER localization as potential classifiers of ccRCC tumors
por: Wrzesiński, Tomasz, et al.
Publicado: (2015)

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism
por: Du, Weinan, et al.
Publicado: (2017)

Integrative Analysis of DNA Methylation Identified 12 Signature Genes Specific to Metastatic ccRCC
por: Qian, Siwei, et al.
Publicado: (2020)

Integrative -omics and HLA-ligandomics analysis to identify novel drug targets for ccRCC immunotherapy
por: Reustle, Anna, et al.
Publicado: (2020)

Transcriptional Profiling Reveals Kidney Neutrophil Heterogeneity in Both Healthy People and ccRCC Patients
por: Meng, Yiliang, et al.
Publicado: (2021)

The Hippo pathway effector YAP inhibits HIF2 signaling and ccRCC tumor growth
por: Li, Xu, et al.
Publicado: (2022)

Establishment of a ccRCC patient-derived chick chorioallantoic membrane model for drug testing
por: Charbonneau, Martine, et al.
Publicado: (2022)

Expression of RSK4, CD44 and MMP-9 is upregulated and positively correlated in metastatic ccRCC
por: Ma, Jing, et al.
Publicado: (2020)

Analysis of dual energy spectral CT and pathological grading of clear cell renal cell carcinoma (ccRCC)
por: Wei, Jinyan, et al.
Publicado: (2018)

Bioinformatics analysis of KLF2 as a potential prognostic factor in ccRCC and association with epithelial-mesenchymal transition
por: Hu, Fangfang, et al.
Publicado: (2022)

An immunotherapy response prediction model derived from proliferative CD4(+) T cells and antigen-presenting monocytes in ccRCC
por: Zheng, Kun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ffm0a6qhkq2h7tna4tf11mpi1p