Cargando…

TNF-α induces AQP4 overexpression in astrocytes through the NF-κB pathway causing cellular edema and apoptosis

Aquaporin 4 (AQP4) is highly expressed on astrocytes and is critical for controlling brain water transport in neurological diseases. Tumor necrosis factor (TNF)-α is a common cytokine found in disease microenvironment. The aim of the present study was to determine whether TNF-α can regulate the expr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Hong, Ai, Li, Zhang, Baoyue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2022
Materias:	Cell Death & Injury
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935387/ https://www.ncbi.nlm.nih.gov/pubmed/35260880 http://dx.doi.org/10.1042/BSR20212224

Ejemplares similares

Exosomes derived from circRNA Rtn4-modified BMSCs attenuate TNF-α-induced cytotoxicity and apoptosis in murine MC3T3-E1 cells by sponging miR-146a
por: Cao, Guijun, et al.
Publicado: (2020)

CTRP3 ameliorates cerulein-induced severe acute pancreatitis in mice via SIRT1/NF-κB/p53 axis
por: Lv, Chunyang, et al.
Publicado: (2020)

Knockdown of TRIM52 alleviates LPS-induced inflammatory injury in human periodontal ligament cells through the TLR4/NF-κB pathway
por: Liu, Peng, et al.
Publicado: (2020)

The effect of copy number on α-synuclein’s toxicity and its protective role in Bax-induced apoptosis, in yeast
por: Akintade, Damilare D., et al.
Publicado: (2020)

Mechanisms of TNF-independent RIPK3-mediated cell death
por: Tummers, Bart, et al.
Publicado: (2022)

A paradox: Fe(2+)-containing agents decreased ROS and apoptosis induced by CoNPs in vascular endothelial cells by inhibiting HIF-1α
por: Zhu, Wenfeng, et al.
Publicado: (2021)

Overexpression of TGR5 alleviates myocardial ischemia/reperfusion injury via AKT/GSK-3β mediated inflammation and mitochondrial pathway
por: Li, Junzhi, et al.
Publicado: (2020)

Mitochondrial protein MPV17 promotes β-cell apoptosis in diabetogenesis
por: Tang, Qiaoli, et al.
Publicado: (2023)

Overexpression of NMNAT3 improves mitochondrial function and enhances antioxidative stress capacity of bone marrow mesenchymal stem cells via the NAD(+)-Sirt3 pathway
por: Wang, Tao, et al.
Publicado: (2022)

Anti-apoptosis mechanism of triptolide based on network pharmacology in focal segmental glomerulosclerosis rats
por: Li, Yayu, et al.
Publicado: (2020)

Myrrh induces the apoptosis and inhibits the proliferation and migration of gastric cancer cells through down-regulating cyclooxygenase-2 expression
por: Sun, Mengxue, et al.
Publicado: (2020)

Up-regulated MCPIP1 in abdominal aortic aneurysm is associated with vascular smooth muscle cell apoptosis and MMPs production
por: Xue, Ming, et al.
Publicado: (2019)

Akt mediates 17β-estradiol and/or estrogen receptor-α inhibition of LPS-induced tumor necresis factor-α expression and myocardial cell apoptosis by suppressing the JNK1/2-NFκB pathway
por: Liu, Chung-Jung, et al.
Publicado: (2009)

Thousand and one kinase 1 protects MCAO-induced cerebral ischemic stroke in rats by decreasing apoptosis and pro-inflammatory factors
por: Li, Jiahui, et al.
Publicado: (2019)

Cyclophilin A inhibits A549 cell oxidative stress and apoptosis by modulating the PI3K/Akt/mTOR signaling pathway
por: Ma, Zhenling, et al.
Publicado: (2021)

CircSERPINE2 weakens IL-1β-caused apoptosis and extracellular matrix degradation of chondrocytes by regulating miR-495/TGFBR2 axis
por: Zhang, Qingpu, et al.
Publicado: (2020)

2,5-Hexanedione induced apoptosis in rat spinal cord neurons and VSC4.1 cells via the proNGF/p75NTR and JNK pathways
por: Luo, Mengxin, et al.
Publicado: (2021)

Ma xing shi gan decoction eliminates PM2.5-induced lung injury by reducing pulmonary cell apoptosis through Akt/mTOR/p70S6K pathway in rats
por: Wang, Yefang, et al.
Publicado: (2020)

Immunotherapy of COVID-19 with poly (ADP-ribose) polymerase inhibitors: starting with nicotinamide
por: Badawy, Abdulla A.-B.
Publicado: (2020)

UCH-L1 inhibitor LDN-57444 hampers mouse oocyte maturation by regulating oxidative stress and mitochondrial function and reducing ERK1/2 expression
por: Yuan, Pan, et al.
Publicado: (2020)

Attenuating ischemia/reperfusion injury in rat cardiac transplantation by intracoronary infusion with siRNA cocktail solution
por: Yang, Bo, et al.
Publicado: (2020)

Evaluation of epithelial progenitor cells and growth factors in a preclinical model of wound healing induced by mesenchymal stromal cells
por: Ramos-Gonzalez, Giselle, et al.
Publicado: (2020)

Potential antiviral agents of Rosmarinus officinalis extract against herpes viruses 1 and 2
por: AL-Megrin, Wafa A., et al.
Publicado: (2020)

Mechanism of N-acetylcysteine in alleviating diabetic myocardial ischemia reperfusion injury by regulating PTEN/Akt pathway through promoting DJ-1
por: Li, Wenyuan, et al.
Publicado: (2020)

The roles of long noncoding RNAs in myocardial pathophysiology
por: Chen, Cheng, et al.
Publicado: (2019)

miR-206 inhibits osteogenic differentiation of bone marrow mesenchymal stem cells by targetting glutaminase
por: Chen, Ying, et al.
Publicado: (2019)

Couplet medicines of leech and centipede granules improve erectile dysfunction via inactivation of the CaSR/PLC/PKC signaling in streptozotocin-induced diabetic rats
por: Ma, Jian Xiong, et al.
Publicado: (2020)

The dietary flavonoid isoliquiritigenin is a potent cytotoxin for human neuroblastoma cells
por: Alshangiti, Amnah M., et al.
Publicado: (2019)

Prostaglandin E1 protects cardiomyocytes against hypoxia-reperfusion induced injury via the miR-21-5p/FASLG axis
por: Tang, Mingxiang, et al.
Publicado: (2019)

Heat stress modulates differential response in skin fibroblast cells of native cattle (Bos indicus) and riverine buffaloes (Bubalus bubalis)
por: Shandilya, Umesh K., et al.
Publicado: (2020)

BTXA regulates the epithelial–mesenchymal transition and autophagy of keloid fibroblasts via modulating miR-1587/miR-2392 targeted ZEB2
por: Hou, Zhanying, et al.
Publicado: (2019)

MiR-760 enhances sensitivity of pancreatic cancer cells to gemcitabine through modulating Integrin β1
por: Yang, Dejun, et al.
Publicado: (2019)

Per2 attenuates LPS-induced chondrocyte injury through the PTEN/PI3K/Akt signalling pathway
por: Zhao, Yu, et al.
Publicado: (2020)

Matrine regulates H(2)O(2)-induced oxidative stress through long non-coding RNA HOTAIR/miR-106b-5p axis via AKT and STAT3 pathways
por: Xu, Guanxue, et al.
Publicado: (2020)

TLR4-mediated pyroptosis in human hepatoma-derived HuH-7 cells induced by a branched-chain polyunsaturated fatty acid, geranylgeranoic acid
por: Yabuta, Suemi, et al.
Publicado: (2020)

Dexmedetomidine alleviated neuropathic pain in dorsal root ganglion neurons by inhibition of anaerobic glycolysis activity and enhancement of ROS tolerance
por: Liu, Peibin, et al.
Publicado: (2020)

The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice
por: Zhu, Shengyun, et al.
Publicado: (2021)

Cannabidiol modulation of oxidative stress and signalling
por: Pereira, Sónia R., et al.
Publicado: (2021)

Responses and coping methods of different testicular cell types to heat stress: overview and perspectives
por: Cai, Hui, et al.
Publicado: (2021)

Neuroprotection of retinal ganglion cells in vivo using the activation of the endogenous cannabinoid signaling system in mammalian eyes
por: Maguire, Greg, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vss1o20c63aq5p3pneod7n42ui