MUlticenter STudy of tissue plasminogen activator (alteplase) use in COVID‐19 severe respiratory failure (MUST COVID): A retrospective cohort study

BACKGROUND: Few therapies exist to treat severe COVID‐19 respiratory failure once it develops. Given known diffuse pulmonary microthrombi on autopsy studies of COVID‐19 patients, we hypothesized that tissue plasminogen activator (tPA) may improve pulmonary function in COVID‐19 respiratory failure. M...

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Detalles Bibliográficos
Autores principales: Barrett, Christopher D., Moore, Hunter B., Moore, Ernest E., Benjamin Christie, Dudley, Orfanos, Sarah, Anez‐Bustillos, Lorenzo, Jhunjhunwala, Rashi, Hussain, Sabiha, Shaefi, Shahzad, Wang, Janice, Hajizadeh, Negin, Baedorf‐Kassis, Elias N., Al‐Shammaa, Ammar, Capers, Krystal, Banner‐Goodspeed, Valerie, Wright, Franklin L., Bull, Todd, Moore, Peter K., Nemec, Hannah, Thomas Buchanan, John, Nonnemacher, Cory, Rajcooar, Natalie, Ramdeo, Ramona, Yacoub, Mena, Guevara, Ana, Espinal, Aileen, Hattar, Laith, Moraco, Andrew, McIntyre, Robert, Talmor, Daniel S., Sauaia, Angela, Yaffe, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935535/
https://www.ncbi.nlm.nih.gov/pubmed/35341072
http://dx.doi.org/10.1002/rth2.12669

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