Solamargine induces hepatocellular carcinoma cell apoptosis and autophagy via inhibiting LIF/miR-192-5p/CYR61/Akt signaling pathways and eliciting immunostimulatory tumor microenvironment

Hepatocellular carcinoma (HCC) is well-known to be a highly prevalent malignant tumor, but the treatment of this pathological state has been still challenging. Solamargine (SM), a traditional Chinese herb-derived compound, has been widely reported to possess multiple antitumor properties. However, w...

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Detalles Bibliográficos
Autores principales: Yin, Shuangshuang, Jin, Wenke, Qiu, Yuling, Fu, Leilei, Wang, Tao, Yu, Haiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935708/
https://www.ncbi.nlm.nih.gov/pubmed/35313929
http://dx.doi.org/10.1186/s13045-022-01248-w

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