Cargando…
Propagation of tau and α-synuclein in the brain: therapeutic potential of the glymphatic system
Many neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease, are characterised by the accumulation of misfolded protein deposits in the brain, leading to a progressive destabilisation of the neuronal network and neuronal death. Among the proteins that can abnormally accumu...
Autores principales: | Lopes, Douglas M., Llewellyn, Sophie K., Harrison, Ian F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935752/ https://www.ncbi.nlm.nih.gov/pubmed/35314000 http://dx.doi.org/10.1186/s40035-022-00293-2 |
Ejemplares similares
-
Propagation of pathological α-synuclein in marmoset brain
por: Shimozawa, Aki, et al.
Publicado: (2017) -
Impaired glymphatic function and clearance of tau in an Alzheimer’s disease model
por: Harrison, Ian F, et al.
Publicado: (2020) -
Glymphatic system clears extracellular tau and protects from tau aggregation and neurodegeneration
por: Ishida, Kazuhisa, et al.
Publicado: (2022) -
Initiation and propagation of α-synuclein aggregation in the nervous system
por: Hijaz, Baraa A., et al.
Publicado: (2020) -
α-Synuclein modulates tau spreading in mouse brains
por: Bassil, Fares, et al.
Publicado: (2020)