Association of recurrent mutations in BRCA1, BRCA2, RAD51C, PALB2, and CHEK2 with the risk of borderline ovarian tumor

BACKGROUND: There are several genes associated with ovarian cancer risk. Molecular changes in borderline ovarian tumor (BOT) indicate linkage of this disease to type I ovarian tumors (low-grade ovarian carcinomas). This study determined the prevalence and association of mutations in BRCA1, BRCA2, PA...

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Detalles Bibliográficos
Autores principales: Ogrodniczak, Alicja, Menkiszak, Janusz, Gronwald, Jacek, Tomiczek-Szwiec, Joanna, Szwiec, Marek, Cybulski, Cezary, Dębniak, Tadeusz, Huzarski, Tomasz, Tołoczko-Grabarek, Aleksandra, Byrski, Tomasz, Białkowska, Katarzyna, Prajzendanc, Karolina, Baszuk, Piotr, Lubiński, Jan, Jakubowska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935754/
https://www.ncbi.nlm.nih.gov/pubmed/35313928
http://dx.doi.org/10.1186/s13053-022-00218-0

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