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Normal amygdala morphology in dissociative identity disorder

Studies investigating the structure of the amygdala in relation to dissociation in psychiatric disorders are limited and have reported normal or preserved, increased or decreased global volumes. Thus, a more detailed investigation of the amygdala is warranted. Amygdala global and subregional volumes...

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Autores principales: Reinders, Antje A. T. S., Dimitrova, Lora I., Schlumpf, Yolanda R., Vissia, Eline M., Nijenhuis, Ellert R. S., Jäncke, Lutz, Chalavi, Sima, Veltman, Dick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935907/
https://www.ncbi.nlm.nih.gov/pubmed/35287776
http://dx.doi.org/10.1192/bjo.2022.36
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author Reinders, Antje A. T. S.
Dimitrova, Lora I.
Schlumpf, Yolanda R.
Vissia, Eline M.
Nijenhuis, Ellert R. S.
Jäncke, Lutz
Chalavi, Sima
Veltman, Dick J.
author_facet Reinders, Antje A. T. S.
Dimitrova, Lora I.
Schlumpf, Yolanda R.
Vissia, Eline M.
Nijenhuis, Ellert R. S.
Jäncke, Lutz
Chalavi, Sima
Veltman, Dick J.
author_sort Reinders, Antje A. T. S.
collection PubMed
description Studies investigating the structure of the amygdala in relation to dissociation in psychiatric disorders are limited and have reported normal or preserved, increased or decreased global volumes. Thus, a more detailed investigation of the amygdala is warranted. Amygdala global and subregional volumes were compared between individuals with dissociative identity disorder (DID: n = 32) and healthy controls (n = 42). Analyses of covariance did not show volumetric differences between the DID and control groups. Although several unknowns make it challenging to interpret our findings, we propose that the finding of normal amygdala volume is a genuine finding because other studies using this data-set have presented robust morphological aberrations in relation to the diagnosis of DID.
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spelling pubmed-89359072022-04-08 Normal amygdala morphology in dissociative identity disorder Reinders, Antje A. T. S. Dimitrova, Lora I. Schlumpf, Yolanda R. Vissia, Eline M. Nijenhuis, Ellert R. S. Jäncke, Lutz Chalavi, Sima Veltman, Dick J. BJPsych Open Short Report Studies investigating the structure of the amygdala in relation to dissociation in psychiatric disorders are limited and have reported normal or preserved, increased or decreased global volumes. Thus, a more detailed investigation of the amygdala is warranted. Amygdala global and subregional volumes were compared between individuals with dissociative identity disorder (DID: n = 32) and healthy controls (n = 42). Analyses of covariance did not show volumetric differences between the DID and control groups. Although several unknowns make it challenging to interpret our findings, we propose that the finding of normal amygdala volume is a genuine finding because other studies using this data-set have presented robust morphological aberrations in relation to the diagnosis of DID. Cambridge University Press 2022-03-15 /pmc/articles/PMC8935907/ /pubmed/35287776 http://dx.doi.org/10.1192/bjo.2022.36 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Report
Reinders, Antje A. T. S.
Dimitrova, Lora I.
Schlumpf, Yolanda R.
Vissia, Eline M.
Nijenhuis, Ellert R. S.
Jäncke, Lutz
Chalavi, Sima
Veltman, Dick J.
Normal amygdala morphology in dissociative identity disorder
title Normal amygdala morphology in dissociative identity disorder
title_full Normal amygdala morphology in dissociative identity disorder
title_fullStr Normal amygdala morphology in dissociative identity disorder
title_full_unstemmed Normal amygdala morphology in dissociative identity disorder
title_short Normal amygdala morphology in dissociative identity disorder
title_sort normal amygdala morphology in dissociative identity disorder
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935907/
https://www.ncbi.nlm.nih.gov/pubmed/35287776
http://dx.doi.org/10.1192/bjo.2022.36
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