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A broad and potent neutralization epitope in SARS-related coronaviruses
Many neutralizing antibodies (nAbs) elicited to ancestral SARS-CoV-2 through natural infection and vaccination generally have reduced effectiveness to SARS-CoV-2 variants. Here we show therapeutic antibody ADG20 is able to neutralize all SARS-CoV-2 variants of concern (VOCs) including Omicron (B.1.1...
Autores principales: | Yuan, Meng, Zhu, Xueyong, He, Wan-ting, Zhou, Panpan, Kaku, Chengzi I., Capozzola, Tazio, Zhu, Connie Y., Yu, Xinye, Liu, Hejun, Yu, Wenli, Hua, Yuanzi, Tien, Henry, Peng, Linghang, Song, Ge, Cottrell, Christopher A., Schief, William R., Nemazee, David, Walker, Laura M., Andrabi, Raiees, Burton, Dennis R., Wilson, Ian A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936108/ https://www.ncbi.nlm.nih.gov/pubmed/35313576 http://dx.doi.org/10.1101/2022.03.13.484037 |
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