A broad and potent neutralization epitope in SARS-related coronaviruses

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Many neutralizing antibodies (nAbs) elicited to ancestral SARS-CoV-2 through natural infection and vaccination generally have reduced effectiveness to SARS-CoV-2 variants. Here we show therapeutic antibody ADG20 is able to neutralize all SARS-CoV-2 variants of concern (VOCs) including Omicron (B.1.1...

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Detalles Bibliográficos
Autores principales: Yuan, Meng, Zhu, Xueyong, He, Wan-ting, Zhou, Panpan, Kaku, Chengzi I., Capozzola, Tazio, Zhu, Connie Y., Yu, Xinye, Liu, Hejun, Yu, Wenli, Hua, Yuanzi, Tien, Henry, Peng, Linghang, Song, Ge, Cottrell, Christopher A., Schief, William R., Nemazee, David, Walker, Laura M., Andrabi, Raiees, Burton, Dennis R., Wilson, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936108/
https://www.ncbi.nlm.nih.gov/pubmed/35313576
http://dx.doi.org/10.1101/2022.03.13.484037
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