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Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single cell resolution

Synthetic glucocorticoids, such as dexamethasone, have been used as treatment for many immune conditions, such as asthma and more recently severe COVID-19. Single cell data can capture more fine-grained details on transcriptional variability and dynamics to gain a better understanding of the molecul...

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Detalles Bibliográficos
Autores principales: Resztak, Justyna A, Wei, Julong, Zilioli, Samuele, Sendler, Edward, Alazizi, Adnan, Mair-Meijers, Henriette E, Wu, Peijun, Wen, Xiaoquan, Slatcher, Richard B, Zhou, Xiang, Luca, Francesca, Pique-Regi, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936121/
https://www.ncbi.nlm.nih.gov/pubmed/35313584
http://dx.doi.org/10.1101/2021.09.30.462672