Variation in CFTR-dependent ‘β-sweating’ among healthy adults

The genetic disease cystic fibrosis (CF) results when mutations in the gene for the anion channel CFTR reduce CFTR’s activity below a critical level. CFTR activity = N·P(O)·γ (number of channels x open probability x channel conductance). Small molecules are now available that partially restore CFTR...

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Detalles Bibliográficos
Autores principales: DeRose, Lesje, Kim, Jeeyeon, Farahmand, Miesha, Shinbashi, Meagan Y., Joo, Nam Soo, Wine, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936459/
https://www.ncbi.nlm.nih.gov/pubmed/35312728
http://dx.doi.org/10.1371/journal.pone.0265432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936459/
https://www.ncbi.nlm.nih.gov/pubmed/35312728
http://dx.doi.org/10.1371/journal.pone.0265432

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