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Variation in CFTR-dependent ‘β-sweating’ among healthy adults

The genetic disease cystic fibrosis (CF) results when mutations in the gene for the anion channel CFTR reduce CFTR’s activity below a critical level. CFTR activity = N·P(O)·γ (number of channels x open probability x channel conductance). Small molecules are now available that partially restore CFTR...

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Detalles Bibliográficos
Autores principales:	DeRose, Lesje, Kim, Jeeyeon, Farahmand, Miesha, Shinbashi, Meagan Y., Joo, Nam Soo, Wine, Jeffrey J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936459/ https://www.ncbi.nlm.nih.gov/pubmed/35312728 http://dx.doi.org/10.1371/journal.pone.0265432

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