Cargando…
A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease
Neurodegenerative disorders refer to a group of diseases commonly associated with abnormal protein accumulation and aggregation in the central nervous system. However, the exact role of protein aggregation in the pathophysiology of these disorders remains unclear. This gap in knowledge is due to the...
Autores principales: | Bérard, Morgan, Sheta, Razan, Malvaut, Sarah, Rodriguez-Aller, Raquel, Teixeira, Maxime, Idi, Walid, Turmel, Roxanne, Alpaugh, Melanie, Dubois, Marilyn, Dahmene, Manel, Salesse, Charleen, Lamontagne-Proulx, Jérôme, St-Pierre, Marie-Kim, Tavassoly, Omid, Luo, Wen, Del Cid-Pellitero, Esther, Qazi, Raza, Jeong, Jae-Woong, Durcan, Thomas M., Vallières, Luc, Tremblay, Marie-Eve, Soulet, Denis, Lévesque, Martin, Cicchetti, Francesca, Fon, Edward A., Saghatelyan, Armen, Oueslati, Abid |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936469/ https://www.ncbi.nlm.nih.gov/pubmed/35263320 http://dx.doi.org/10.1371/journal.pbio.3001578 |
Ejemplares similares
-
Alpha-Synuclein and the Endolysosomal System in Parkinson’s Disease: Guilty by Association
por: Teixeira, Maxime, et al.
Publicado: (2021) -
Optimized protocol for the generation of functional human induced-pluripotent-stem-cell-derived dopaminergic neurons
por: Sheta, Razan, et al.
Publicado: (2023) -
Combining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neurons
por: Sheta, Razan, et al.
Publicado: (2022) -
The Role of Adult-Born Neurons in the Constantly Changing Olfactory Bulb Network
por: Malvaut, Sarah, et al.
Publicado: (2016) -
Non-invasive systemic viral delivery of human alpha-synuclein mimics selective and progressive neuropathology of Parkinson’s disease in rodent brains
por: Bérard, Morgan, et al.
Publicado: (2023)