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A novel anti‐c‐Kit antibody–drug conjugate to treat wild‐type and activating‐mutant c‐Kit‐positive tumors
c‐Kit overexpression and activating mutations, which are reported in various cancers, including gastrointestinal stromal tumor (GIST), small‐cell lung cancer (SCLC), acute myeloid leukemia, acral melanoma, and systemic mastocytosis (SM), confer resistance to tyrosine kinase inhibitors (TKIs). To ove...
Autores principales: | Kim, Jin‐Ock, Kim, Kwang‐Hyeok, Baek, Eun Ji, Park, Bomi, So, Min Kyung, Ko, Byoung Joon, Ko, Han‐Jik, Park, Sang Gyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936518/ https://www.ncbi.nlm.nih.gov/pubmed/34407310 http://dx.doi.org/10.1002/1878-0261.13084 |
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