Endothelial barrier function is co-regulated at vessel bifurcations by fluid forces and sphingosine-1-phosphate

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid mediator of endothelial barrier function. Prior studies have implicated mechanical stimulation due to intravascular laminar shear stress in co-regulating S1P signaling in endothelial cells (ECs). Yet, vascular networks in vivo consist of vess...

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Detalles Bibliográficos
Autores principales: Akbari, Ehsan, Spychalski, Griffin B., Menyhert, Miles M., Rangharajan, Kaushik K., Tinapple, Joseph W., Prakash, Shaurya, Song, Jonathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936769/
https://www.ncbi.nlm.nih.gov/pubmed/35317095
http://dx.doi.org/10.1016/j.bbiosy.2021.100020

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