A back-up source of microtubules for the midbody during cytokinesis

During cytokinesis, microtubules become compacted into a dense midbody prior to abscission. Using genetic perturbations and imaging of C. elegans zygotes, Hirsch et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202011085) uncover an unexpected source of microtubules that can populate the midb...

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Detalles Bibliográficos
Autor principal: Hickson, Gilles R.X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8937023/
https://www.ncbi.nlm.nih.gov/pubmed/35191950
http://dx.doi.org/10.1083/jcb.202201028
Descripción
Sumario:During cytokinesis, microtubules become compacted into a dense midbody prior to abscission. Using genetic perturbations and imaging of C. elegans zygotes, Hirsch et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202011085) uncover an unexpected source of microtubules that can populate the midbody when central spindle microtubules are missing.

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