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New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)

Our previous study verified that the waste skin of cocoa (Theobroma cacao L) fruit or waste cocoa pod husks had the efficacy to overcome hair loss or alopecia. This study aims to determine the formula and activity of hair cream of cocoa pod peel water fraction, which is effective in stimulating hair...

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Autores principales: Mustarichie, Resmi, Hasanah, Aliya Nur, Wilar, Gofarana, Gozali, Dolih, Saptarini, Nyi Mekar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938051/
https://www.ncbi.nlm.nih.gov/pubmed/35320948
http://dx.doi.org/10.1155/2022/2299725
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author Mustarichie, Resmi
Hasanah, Aliya Nur
Wilar, Gofarana
Gozali, Dolih
Saptarini, Nyi Mekar
author_facet Mustarichie, Resmi
Hasanah, Aliya Nur
Wilar, Gofarana
Gozali, Dolih
Saptarini, Nyi Mekar
author_sort Mustarichie, Resmi
collection PubMed
description Our previous study verified that the waste skin of cocoa (Theobroma cacao L) fruit or waste cocoa pod husks had the efficacy to overcome hair loss or alopecia. This study aims to determine the formula and activity of hair cream of cocoa pod peel water fraction, which is effective in stimulating hair growth. Activity testing uses the modified Tanaka method. The results showed that the cocoa husk wastewater fraction could be formulated into hair cream, but there were changes in viscosity and pH after the freeze-thaw test, but still within the allowed limit. The hair cream water fraction gel stimulated hair growth activity based on the hair length data with a significant difference in concentration of the preparation. The best activity in hair cream preparation was at 12.5% concentration. In addition, there were no signs of irritation to the rabbit's skin where hair cream preparation was applied. The results of this study indicated that cocoa fruit peel cream can be used for antialopecia treatments.
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spelling pubmed-89380512022-03-22 New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.) Mustarichie, Resmi Hasanah, Aliya Nur Wilar, Gofarana Gozali, Dolih Saptarini, Nyi Mekar ScientificWorldJournal Research Article Our previous study verified that the waste skin of cocoa (Theobroma cacao L) fruit or waste cocoa pod husks had the efficacy to overcome hair loss or alopecia. This study aims to determine the formula and activity of hair cream of cocoa pod peel water fraction, which is effective in stimulating hair growth. Activity testing uses the modified Tanaka method. The results showed that the cocoa husk wastewater fraction could be formulated into hair cream, but there were changes in viscosity and pH after the freeze-thaw test, but still within the allowed limit. The hair cream water fraction gel stimulated hair growth activity based on the hair length data with a significant difference in concentration of the preparation. The best activity in hair cream preparation was at 12.5% concentration. In addition, there were no signs of irritation to the rabbit's skin where hair cream preparation was applied. The results of this study indicated that cocoa fruit peel cream can be used for antialopecia treatments. Hindawi 2022-03-14 /pmc/articles/PMC8938051/ /pubmed/35320948 http://dx.doi.org/10.1155/2022/2299725 Text en Copyright © 2022 Resmi Mustarichie et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Mustarichie, Resmi
Hasanah, Aliya Nur
Wilar, Gofarana
Gozali, Dolih
Saptarini, Nyi Mekar
New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)
title New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)
title_full New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)
title_fullStr New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)
title_full_unstemmed New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)
title_short New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)
title_sort new hair growth cream formulation with cocoa pod peel (theobroma cacao l.)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938051/
https://www.ncbi.nlm.nih.gov/pubmed/35320948
http://dx.doi.org/10.1155/2022/2299725
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