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Rapid and parallel adaptive mutations in spike S1 drive clade success in SARS-CoV-2

The SARS-CoV-2 pandemic has resulted in numerous virus variants, some of which have altered receptor-binding or antigenic phenotypes. Here, we quantify the degree to which adaptive evolution is driving the accumulation of mutations across the genome. We correlate clade growth with mutation accumulat...

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Detalles Bibliográficos
Autores principales: Kistler, Kathryn E., Huddleston, John, Bedford, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938189/
https://www.ncbi.nlm.nih.gov/pubmed/35364015
http://dx.doi.org/10.1016/j.chom.2022.03.018