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Rapid and parallel adaptive mutations in spike S1 drive clade success in SARS-CoV-2
The SARS-CoV-2 pandemic has resulted in numerous virus variants, some of which have altered receptor-binding or antigenic phenotypes. Here, we quantify the degree to which adaptive evolution is driving the accumulation of mutations across the genome. We correlate clade growth with mutation accumulat...
Autores principales: | Kistler, Kathryn E., Huddleston, John, Bedford, Trevor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938189/ https://www.ncbi.nlm.nih.gov/pubmed/35364015 http://dx.doi.org/10.1016/j.chom.2022.03.018 |
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