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The epidemiology and outcomes of adult in-hospital cardiac arrest in a high-income developing country

AIM: In-Hospital Cardiac Arrest (IHCA) is a significant burden on healthcare worldwide. Outcomes of IHCA are worse in developing countries compared with developed ones. We aimed to study the epidemiology and factors determining outcomes in adult IHCA in a high income developing country. METHODS: We...

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Autores principales: Alao, David O., Mohammed, Nada A., Hukan, Yaman O., Al Neyadi, Maitha, Jummani, Zia, Dababneh, Emad H., Cevik, Arif A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938330/
https://www.ncbi.nlm.nih.gov/pubmed/35330757
http://dx.doi.org/10.1016/j.resplu.2022.100220
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author Alao, David O.
Mohammed, Nada A.
Hukan, Yaman O.
Al Neyadi, Maitha
Jummani, Zia
Dababneh, Emad H.
Cevik, Arif A.
author_facet Alao, David O.
Mohammed, Nada A.
Hukan, Yaman O.
Al Neyadi, Maitha
Jummani, Zia
Dababneh, Emad H.
Cevik, Arif A.
author_sort Alao, David O.
collection PubMed
description AIM: In-Hospital Cardiac Arrest (IHCA) is a significant burden on healthcare worldwide. Outcomes of IHCA are worse in developing countries compared with developed ones. We aimed to study the epidemiology and factors determining outcomes in adult IHCA in a high income developing country. METHODS: We abstracted prospectively collected data of adult patients admitted to our institution over a three-year period who suffered a cardiac arrest. We analysed patient demographics, arrest characteristics, including response time, initial rhythm and code duration. Pre-arrest vital signs, primary diagnoses, discharge and functional status, were obtained from the patients' electronic medical records. RESULTS: A total of 447 patients were studied. The IHCA rate was 8.6/1000 hospital admissions. Forty percent (40%) achieved ROSC with an overall survival to discharge rate of 10.8%, of which 59% had a good functional outcome, with a cerebral performance category score of 1 or 2. Fifty-four percent (54%) of patients had IHCA attributed to causes other than cardiac or respiratory. Admission Glasgow Coma Scale (GCS), shockable rhythm and short code duration were significantly associated with survival (p < 0.001). CONCLUSION: A combination of patient and system-related factors, such as the underlying cause of cardiac arrest and a lack of DNAR policy, may explain the reduced survival rate in our setting compared with developed countries.
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spelling pubmed-89383302022-03-23 The epidemiology and outcomes of adult in-hospital cardiac arrest in a high-income developing country Alao, David O. Mohammed, Nada A. Hukan, Yaman O. Al Neyadi, Maitha Jummani, Zia Dababneh, Emad H. Cevik, Arif A. Resusc Plus Clinical Paper AIM: In-Hospital Cardiac Arrest (IHCA) is a significant burden on healthcare worldwide. Outcomes of IHCA are worse in developing countries compared with developed ones. We aimed to study the epidemiology and factors determining outcomes in adult IHCA in a high income developing country. METHODS: We abstracted prospectively collected data of adult patients admitted to our institution over a three-year period who suffered a cardiac arrest. We analysed patient demographics, arrest characteristics, including response time, initial rhythm and code duration. Pre-arrest vital signs, primary diagnoses, discharge and functional status, were obtained from the patients' electronic medical records. RESULTS: A total of 447 patients were studied. The IHCA rate was 8.6/1000 hospital admissions. Forty percent (40%) achieved ROSC with an overall survival to discharge rate of 10.8%, of which 59% had a good functional outcome, with a cerebral performance category score of 1 or 2. Fifty-four percent (54%) of patients had IHCA attributed to causes other than cardiac or respiratory. Admission Glasgow Coma Scale (GCS), shockable rhythm and short code duration were significantly associated with survival (p < 0.001). CONCLUSION: A combination of patient and system-related factors, such as the underlying cause of cardiac arrest and a lack of DNAR policy, may explain the reduced survival rate in our setting compared with developed countries. Elsevier 2022-03-19 /pmc/articles/PMC8938330/ /pubmed/35330757 http://dx.doi.org/10.1016/j.resplu.2022.100220 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Clinical Paper
Alao, David O.
Mohammed, Nada A.
Hukan, Yaman O.
Al Neyadi, Maitha
Jummani, Zia
Dababneh, Emad H.
Cevik, Arif A.
The epidemiology and outcomes of adult in-hospital cardiac arrest in a high-income developing country
title The epidemiology and outcomes of adult in-hospital cardiac arrest in a high-income developing country
title_full The epidemiology and outcomes of adult in-hospital cardiac arrest in a high-income developing country
title_fullStr The epidemiology and outcomes of adult in-hospital cardiac arrest in a high-income developing country
title_full_unstemmed The epidemiology and outcomes of adult in-hospital cardiac arrest in a high-income developing country
title_short The epidemiology and outcomes of adult in-hospital cardiac arrest in a high-income developing country
title_sort epidemiology and outcomes of adult in-hospital cardiac arrest in a high-income developing country
topic Clinical Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938330/
https://www.ncbi.nlm.nih.gov/pubmed/35330757
http://dx.doi.org/10.1016/j.resplu.2022.100220
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