Cargando…

Serum amyloid A1 exacerbates hepatic steatosis via TLR4-mediated NF-κB signaling pathway

OBJECTIVE: Chronic inflammatory response plays a prominent role in obesity-related nonalcoholic fatty liver disease (NAFLD). However, the intrahepatic triggering mechanism of inflammation remains obscure. This study aimed to elucidate the role of serum amyloid A1 (SAA1), an acute-phase response prot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Bin, Wang, Dongdong, Hu, Yunfu, Li, Wenxuan, Liu, Fengjiang, Zhu, Xudong, Li, Xiaoyu, Zhang, Hanwen, Bai, Hui, Yang, Qing, Yang, Xiuna, Ben, Jingjing, Chen, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938331/ https://www.ncbi.nlm.nih.gov/pubmed/35247611 http://dx.doi.org/10.1016/j.molmet.2022.101462

Ejemplares similares

Miltefosine Suppresses Hepatic Steatosis by Activating AMPK Signal Pathway
por: Fang, Ru, et al.
Publicado: (2016)

Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK–NF-κB signaling mediated inflammation
por: Ben, Jingjing, et al.
Publicado: (2019)

Artemisinin Attenuates Amyloid-Induced Brain Inflammation and Memory Impairments by Modulating TLR4/NF-κB Signaling
por: Zhao, Xia, et al.
Publicado: (2022)

TLR4/NF-κB signaling activation in plantar tissue and dorsal root ganglion involves in the development of postoperative pain
por: Xing, Fei, et al.
Publicado: (2018)

Curcumin protects against hepatic ischemia/reperfusion induced injury through inhibiting TLR4/NF-κB pathway
por: Wang, Lu, et al.
Publicado: (2017)

APOC1 exacerbates renal fibrosis through the activation of the NF-κB signaling pathway in IgAN
por: Yu, Kuipeng, et al.
Publicado: (2023)

NEK7 inhibition attenuates Aβ(42)-induced cognitive impairment by regulating TLR4/NF-κB and the NLRP3 inflammasome in mice
por: Li, Peng, et al.
Publicado: (2023)

Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway
por: Li, Chengcheng, et al.
Publicado: (2017)

NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis
por: Maeda, Shin
Publicado: (2010)

Importance of extra- and intracellular domains of TLR1 and TLR2 in NFκB signaling
por: Sandor, Frantisek, et al.
Publicado: (2003)

Chondroprotective and anti‐inflammatory effects of amurensin H by regulating TLR4/Syk/NF‐κB signals
por: Ma, Pei, et al.
Publicado: (2019)

Oxycodone Alleviates Endometrial Injury via the TLR4/NF-κB Pathway
por: Zhu, Aibing, et al.
Publicado: (2022)

Oxymatrine Downregulates TLR4, TLR2, MyD88, and NF-κB and Protects Rat Brains against Focal Ischemia
por: Fan, Hongguang, et al.
Publicado: (2009)

Methane-Rich Saline Counteracts Cholestasis-Induced Liver Damage via Regulating the TLR4/NF-κB/NLRP3 Inflammasome Pathway
por: Li, Zeyu, et al.
Publicado: (2019)

Yiyi Fuzi Baijiang Decoction Alleviates Ulcerative Colitis Partly by Regulating TLR4-Mediated PI3K/Akt and NF-κB Pathways
por: Chen, Liping, et al.
Publicado: (2022)

Phosphorylated α-synuclein aggregated in Schwann cells exacerbates peripheral neuroinflammation and nerve dysfunction in Parkinson’s disease through TLR2/NF-κB pathway
por: Sun, Li, et al.
Publicado: (2021)

Modulation of TLR4/NFκB Pathways in Autoimmune Myocarditis
por: Interdonato, Livia, et al.
Publicado: (2023)

Upregulation of miRNA-140-5p inhibits inflammatory cytokines in acute lung injury through the MyD88/NF-κB signaling pathway by targeting TLR4
por: Yang, Ye, et al.
Publicado: (2018)

Inhibition of uncoupling protein 2 with genipin exacerbates palmitate-induced hepatic steatosis
por: Ma, Shuangtao, et al.
Publicado: (2012)

Mechanism of Probiotic VSL#3 Inhibiting NF-κB and TNF-α on Colitis through TLR4-NF-κB Signal Pathway
por: WANG, Hui, et al.
Publicado: (2019)

Roles of TLR7 in Activation of NF-κB Signaling of Keratinocytes by Imiquimod
por: Li, Zheng Jun, et al.
Publicado: (2013)

Palmitic Acid Promotes Lung Metastasis of Melanomas via the TLR4/TRIF-Peli1-pNF-κB Pathway
por: Zhang, Xuedan, et al.
Publicado: (2022)

Curcumin prevents high-fat diet-induced hepatic steatosis in ApoE(−/−) mice by improving intestinal barrier function and reducing endotoxin and liver TLR4/NF-κB inflammation
por: Feng, Dan, et al.
Publicado: (2019)

rhHMGB1 drives osteoblast migration in a TLR2/TLR4- and NF-κB-dependent manner
por: Li, Ming-Jing, et al.
Publicado: (2016)

Celastrol ameliorates osteoarthritis via regulating TLR2/NF-κB signaling pathway
por: Yang, Guangxia, et al.
Publicado: (2022)

Chlojaponilactone B Attenuates Lipopolysaccharide-Induced Inflammatory Responses by Suppressing TLR4-Mediated ROS Generation and NF-κB Signaling Pathway
por: Ye, Shaoxia, et al.
Publicado: (2019)

mRNA expression of TLR4, TLR9 and NF-κB in a neonatal murine model of necrotizing enterocolitis
por: Yin, Yiyu, et al.
Publicado: (2016)

Exposure to CuO Nanoparticles Mediates NFκB Activation and Enhances Amyloid Precursor Protein Expression
por: Mou, Xiaoyang, et al.
Publicado: (2020)

Andrographolide Suppress Tumor Growth by Inhibiting TLR4/NF-κB Signaling Activation in Insulinoma
por: Zhang, Qian-Qian, et al.
Publicado: (2014)

Apple Polyphenols Decrease Atherosclerosis and Hepatic Steatosis in ApoE(−/−) Mice through the ROS/MAPK/NF-κB Pathway
por: Xu, Zhe-Rong, et al.
Publicado: (2015)

The effect of focal cerebral ischemia-reperfusion injury on TLR4 and NF-κB signaling pathway
por: Chen, Jing, et al.
Publicado: (2018)

Baicalin alleviates collagen-induced arthritis and suppresses TLR2/MYD88/NF-κB p65 signaling in rats and HFLS-RAs
por: Bai, Lin, et al.
Publicado: (2020)

The Role of bFGF in the Excessive Activation of Astrocytes Is Related to the Inhibition of TLR4/NFκB Signals
por: Ye, Libing, et al.
Publicado: (2015)

Serum NF-κBp65, TLR4 as Biomarker for Diagnosis of Preeclampsia
por: Litang, Zhao, et al.
Publicado: (2017)

Astragaloside IV Improves High-Fat Diet–Induced Hepatic Steatosis in Nonalcoholic Fatty Liver Disease Rats by Regulating Inflammatory Factors Level via TLR4/NF-κB Signaling Pathway
por: Liu, Ying-Li, et al.
Publicado: (2021)

Andrographolide Suppress Tumor Growth by Inhibiting TLR4/NF-κB Signaling Activation in Insulinoma: Erratum
por: Zhang, Qian-Qian, et al.
Publicado: (2020)

Hepatic deficiency of selenoprotein S exacerbates hepatic steatosis and insulin resistance
por: Qiao, Lu, et al.
Publicado: (2022)

Chlamydia psittaci PmpD-N Exacerbated Chicken Macrophage Function by Triggering Th2 Polarization and the TLR2/MyD88/NF-κB Signaling Pathway
por: Chu, Jun, et al.
Publicado: (2020)

The TLR4/NF-κB/MAGI-2 signaling pathway mediates postoperative delirium
por: Zhang, Wei, et al.
Publicado: (2022)

Thalidomide Alleviates Pulmonary Fibrosis Induced by Silica in Mice by Inhibiting ER Stress and the TLR4-NF-κB Pathway
por: Li, Yaqian, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_lmas9nktajq3hs226dassgu95n