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Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease

Alzheimer’s disease (AD) is defined by amyloid (A) and tau (T) pathologies, with T better correlated to neurodegeneration (N). However, T and N have complex regional relationships in part related to non-AD factors that influence N. With machine learning, we assessed heterogeneity in (18)F-flortaucip...

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Detalles Bibliográficos
Autores principales: Duong, Michael Tran, Das, Sandhitsu R., Lyu, Xueying, Xie, Long, Richardson, Hayley, Xie, Sharon X., Yushkevich, Paul A., Wolk, David A., Nasrallah, Ilya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938426/
https://www.ncbi.nlm.nih.gov/pubmed/35314672
http://dx.doi.org/10.1038/s41467-022-28941-1

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