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Intranasal delivery of pro-resolving lipid mediators rescues memory and gamma oscillation impairment in App(NL-G-F/NL-G-F) mice

Sustained microglial activation and increased pro-inflammatory signalling cause chronic inflammation and neuronal damage in Alzheimer’s disease (AD). Resolution of inflammation follows neutralization of pathogens and is a response to limit damage and promote healing, mediated by pro-resolving lipid...

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Detalles Bibliográficos
Autores principales:	Emre, Ceren, Arroyo-García, Luis E., Do, Khanh V., Jun, Bokkyoo, Ohshima, Makiko, Alcalde, Silvia Gómez, Cothern, Megan L., Maioli, Silvia, Nilsson, Per, Hjorth, Erik, Fisahn, André, Bazan, Nicolas G., Schultzberg, Marianne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938447/ https://www.ncbi.nlm.nih.gov/pubmed/35314851 http://dx.doi.org/10.1038/s42003-022-03169-3

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