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Thioredoxin interacting protein protects mice from fasting induced liver steatosis by activating ER stress and its downstream signaling pathways

Under normal conditions, fasting results in decreased protein disulfide isomerase (PDI) activity and accumulation of unfolded proteins, leading to the subsequent activation of the unfolded protein response (UPR)/autophagy signaling pathway to eliminate damaged mitochondria. Fasting also induces upre...

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Detalles Bibliográficos
Autores principales:	Miyahara, Hiroyuki, Hasegawa, Kosei, Yashiro, Masato, Ohara, Toshiaki, Fujisawa, Masayoshi, Yoshimura, Teizo, Matsukawa, Akihiro, Tsukahara, Hirokazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938456/ https://www.ncbi.nlm.nih.gov/pubmed/35314758 http://dx.doi.org/10.1038/s41598-022-08791-z

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