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Exogenous lipase administration alters gut microbiota composition and ameliorates Alzheimer’s disease-like pathology in APP/PS1 mice

Alzheimer’s disease (AD) represents the most common form of dementia in the elderly with no available disease modifying treatments. Altered gut microbial composition has been widely acknowledged as a common feature of AD, which potentially contributes to progression or onset of AD. To assess the hyp...

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Detalles Bibliográficos
Autores principales: Menden, Ariane, Hall, Davane, Hahn-Townsend, Coral, Broedlow, Courtney A., Joshi, Utsav, Pearson, Andrew, Crawford, Fiona, Evans, James E., Klatt, Nichole, Crynen, Stefan, Mullan, Michael, Ait-Ghezala, Ghania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938460/
https://www.ncbi.nlm.nih.gov/pubmed/35314754
http://dx.doi.org/10.1038/s41598-022-08840-7