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Fibroblast activation protein activated antifibrotic peptide delivery attenuates fibrosis in mouse models of liver fibrosis

In liver fibrosis, activated hepatic stellate cells are known to overexpress fibroblast activation protein. Here we report a targeted antifibrotic peptide-delivery system in which fibroblast activation protein, which is overexpressed in fibrotic regions of the liver, liberates the antifibrotic pepti...

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Detalles Bibliográficos
Autores principales: Lee, Jaiwoo, Byun, Junho, Shim, Gayong, Oh, Yu-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938482/
https://www.ncbi.nlm.nih.gov/pubmed/35314685
http://dx.doi.org/10.1038/s41467-022-29186-8