A pharmacogenetic interaction analysis of bevacizumab with paclitaxel in advanced breast cancer patients

To investigate pharmacogenetic interactions among VEGF-A, VEGFR-2, IL-8, HIF-1α, EPAS-1, and TSP-1 SNPs and their role on progression-free survival (PFS) in metastatic breast cancer (MBC) patients treated with bevacizumab plus first-line paclitaxel or with paclitaxel alone. Analyses were performed o...

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Detalles Bibliográficos
Autores principales: Coltelli, Luigi, Allegrini, Giacomo, Orlandi, Paola, Finale, Chiara, Fontana, Andrea, Masini, Luna Chiara, Scalese, Marco, Arrighi, Giada, Barletta, Maria Teresa, De Maio, Ermelinda, Banchi, Marta, Fini, Elisabetta, Guidi, Patrizia, Frenzilli, Giada, Donati, Sara, Giovannelli, Simona, Tanganelli, Lucia, Salvadori, Barbara, Livi, Lorenzo, Meattini, Icro, Pazzagli, Ilaria, Di Lieto, Marco, Pistelli, Mirco, Casadei, Virginia, Ferro, Antonella, Cupini, Samanta, Orlandi, Francesca, Francesca, Damiana, Lorenzini, Giulia, Barellini, Leonardo, Falcone, Alfredo, Cosimi, Alessandro, Bocci, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938486/
https://www.ncbi.nlm.nih.gov/pubmed/35314692
http://dx.doi.org/10.1038/s41523-022-00400-6

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