ADARs act as potent regulators of circular transcriptome in cancer

Circular RNAs (circRNAs) are produced by head-to-tail back-splicing which is mainly facilitated by base-pairing of reverse complementary matches (RCMs) in circRNA flanking introns. Adenosine deaminases acting on RNA (ADARs) are known to bind double-stranded RNAs for adenosine to inosine (A-to-I) RNA...

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Detalles Bibliográficos
Autores principales: Shen, Haoqing, An, Omer, Ren, Xi, Song, Yangyang, Tang, Sze Jing, Ke, Xin-Yu, Han, Jian, Tay, Daryl Jin Tai, Ng, Vanessa Hui En, Molias, Fernando Bellido, Pitcheshwar, Priyankaa, Leong, Ka Wai, Tan, Ker-Kan, Yang, Henry, Chen, Leilei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938519/
https://www.ncbi.nlm.nih.gov/pubmed/35314703
http://dx.doi.org/10.1038/s41467-022-29138-2

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