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An RNA-binding protein acts as a major post-transcriptional modulator in Bacillus anthracis

HitRS is a two-component system that responds to cell envelope damage in the human pathogen Bacillus anthracis. Here we identify an RNA-binding protein, KrrA, that regulates HitRS function by modulating the stability of the hitRS mRNA. In addition to hitRS, KrrA binds to over 70 RNAs and, directly o...

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Detalles Bibliográficos
Autores principales: Pi, Hualiang, Weiss, Andy, Laut, Clare L., Grunenwald, Caroline M., Lin, Hannah K., Yi, Xinjie I., Stauff, Devin L., Skaar, Eric P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938561/
https://www.ncbi.nlm.nih.gov/pubmed/35314695
http://dx.doi.org/10.1038/s41467-022-29209-4