Fluorinated Phosphoadenosine 5′-Phosphosulfate Analogues for Continuous Sulfotransferase Activity Monitoring and Inhibitor Screening by (19)F NMR Spectroscopy

[Image: see text] Sulfotransferases (STs) are ubiquitous enzymes that participate in a vast number of biological processes involving sulfuryl group (SO(3)) transfer. 3′-phosphoadenosine 5′-phosphosulfate (PAPS) is the universal ST cofactor, serving as the “active sulfate” source in cells. Herein, we...

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Detalles Bibliográficos
Autores principales: Mlynarska-Cieslak, Agnieszka, Chrominski, Mikolaj, Spiewla, Tomasz, Baranowski, Marek R., Bednarczyk, Marcelina, Jemielity, Jacek, Kowalska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938925/
https://www.ncbi.nlm.nih.gov/pubmed/35196009
http://dx.doi.org/10.1021/acschembio.1c00978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938925/
https://www.ncbi.nlm.nih.gov/pubmed/35196009
http://dx.doi.org/10.1021/acschembio.1c00978

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