CAISC: A software to integrate copy number variations and single nucleotide mutations for genetic heterogeneity profiling and subclone detection by single-cell RNA sequencing

BACKGROUND: Although both copy number variations (CNVs) and single nucleotide variations (SNVs) detected by single-cell RNA sequencing (scRNA-seq) are used to study intratumor heterogeneity and detect clonal groups, a software that integrates these two types of data in the same cells is unavailable....

Descripción completa

Detalles Bibliográficos
Autores principales: Kannan, Jeerthi, Mathews, Liza, Wu, Zhijie, Young, Neal S., Gao, Shouguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939069/
https://www.ncbi.nlm.nih.gov/pubmed/35313800
http://dx.doi.org/10.1186/s12859-022-04625-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939069/
https://www.ncbi.nlm.nih.gov/pubmed/35313800
http://dx.doi.org/10.1186/s12859-022-04625-x

Ejemplares similares