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The innate immune receptor Nlrp12 suppresses autoimmunity to the retina

BACKGROUND: Nod-like receptors (NLRs) are critical to innate immune activation and induction of adaptive T cell responses. Yet, their role in autoinflammatory diseases of the central nervous system (CNS) remains incompletely defined. The NLR, Nlrp12, has been reported to both inhibit and promote neu...

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Detalles Bibliográficos
Autores principales: Lee, Ellen J., Napier, Ruth J., Vance, Emily E., Lashley, Sydney J., Truax, Agnieszka D., Ting, Jenny P., Rosenzweig, Holly L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939070/
https://www.ncbi.nlm.nih.gov/pubmed/35313917
http://dx.doi.org/10.1186/s12974-022-02425-x