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Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension: Association of obesity indicators with ISH

BACKGROUND: Obesity is a well-known modified risk factor for isolated systolic hypertension (ISH), but evidence is lacking regarding whether the combination of anthropometric and lipid indicators could strengthen their correlation with ISH. Therefore, we compared the association of body mass index (...

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Autores principales: Qian, Jian Dong, Li, Xiao Mei, Chen, Dong Shui, Zhu, Jian Qin, Liu, Xing Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939084/
https://www.ncbi.nlm.nih.gov/pubmed/35313806
http://dx.doi.org/10.1186/s12872-022-02564-2
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author Qian, Jian Dong
Li, Xiao Mei
Chen, Dong Shui
Zhu, Jian Qin
Liu, Xing Zhen
author_facet Qian, Jian Dong
Li, Xiao Mei
Chen, Dong Shui
Zhu, Jian Qin
Liu, Xing Zhen
author_sort Qian, Jian Dong
collection PubMed
description BACKGROUND: Obesity is a well-known modified risk factor for isolated systolic hypertension (ISH), but evidence is lacking regarding whether the combination of anthropometric and lipid indicators could strengthen their correlation with ISH. Therefore, we compared the association of body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), visceral adiposity index (VAI), lipid accumulation product index (LAP), and cardiometabolic index (CMI) with ISH. METHODS: A total of 106,248 adults who received routine health screening and did not have diastolic blood pressure ≥ 90 mmHg were recruited in this cross-sectional study. The associations between these indicators and ISH were evaluated using multivariate regression. RESULTS: Each standard deviation (SD) increase in traditional obesity indicators (especially WHR and WHtR) had significantly higher multivariate-adjusted odds ratios (ORs) than each SD increase in lipid-related obesity indicators. In addition, multivariate-adjusted ORs for ISH in the third (vs. the first) tertile of traditional obesity indicators were also significantly higher than those of lipid-related indicators. Moreover, traditional obesity indicators exhibited a higher area under the ROC curve for discriminating ISH than lipid-related obesity indicators. CONCLUSIONS: Traditional obesity indicators were more strongly associated with ISH than lipid-related obesity indicators among Chinese adults. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-022-02564-2.
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spelling pubmed-89390842022-03-23 Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension: Association of obesity indicators with ISH Qian, Jian Dong Li, Xiao Mei Chen, Dong Shui Zhu, Jian Qin Liu, Xing Zhen BMC Cardiovasc Disord Research BACKGROUND: Obesity is a well-known modified risk factor for isolated systolic hypertension (ISH), but evidence is lacking regarding whether the combination of anthropometric and lipid indicators could strengthen their correlation with ISH. Therefore, we compared the association of body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), visceral adiposity index (VAI), lipid accumulation product index (LAP), and cardiometabolic index (CMI) with ISH. METHODS: A total of 106,248 adults who received routine health screening and did not have diastolic blood pressure ≥ 90 mmHg were recruited in this cross-sectional study. The associations between these indicators and ISH were evaluated using multivariate regression. RESULTS: Each standard deviation (SD) increase in traditional obesity indicators (especially WHR and WHtR) had significantly higher multivariate-adjusted odds ratios (ORs) than each SD increase in lipid-related obesity indicators. In addition, multivariate-adjusted ORs for ISH in the third (vs. the first) tertile of traditional obesity indicators were also significantly higher than those of lipid-related indicators. Moreover, traditional obesity indicators exhibited a higher area under the ROC curve for discriminating ISH than lipid-related obesity indicators. CONCLUSIONS: Traditional obesity indicators were more strongly associated with ISH than lipid-related obesity indicators among Chinese adults. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-022-02564-2. BioMed Central 2022-03-21 /pmc/articles/PMC8939084/ /pubmed/35313806 http://dx.doi.org/10.1186/s12872-022-02564-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Qian, Jian Dong
Li, Xiao Mei
Chen, Dong Shui
Zhu, Jian Qin
Liu, Xing Zhen
Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension: Association of obesity indicators with ISH
title Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension: Association of obesity indicators with ISH
title_full Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension: Association of obesity indicators with ISH
title_fullStr Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension: Association of obesity indicators with ISH
title_full_unstemmed Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension: Association of obesity indicators with ISH
title_short Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension: Association of obesity indicators with ISH
title_sort comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension: association of obesity indicators with ish
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939084/
https://www.ncbi.nlm.nih.gov/pubmed/35313806
http://dx.doi.org/10.1186/s12872-022-02564-2
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