Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases

BACKGROUND: Rheumatic heart disease (RHD) remains a major source of morbidity and mortality in developing countries. A deeper insight into the pathogenetic mechanisms underlying RHD could provide opportunities for drug repurposing, guide recommendations for secondary penicillin prophylaxis, and/or i...

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Detalles Bibliográficos
Autores principales: Salie, M. Taariq, Yang, Jing, Ramírez Medina, Carlos R., Zühlke, Liesl J., Chishala, Chishala, Ntsekhe, Mpiko, Gitura, Bernard, Ogendo, Stephen, Okello, Emmy, Lwabi, Peter, Musuku, John, Mtaja, Agnes, Hugo-Hamman, Christopher, El-Sayed, Ahmed, Damasceno, Albertino, Mocumbi, Ana, Bode-Thomas, Fidelia, Yilgwan, Christopher, Amusa, Ganiyu A., Nkereuwem, Esin, Shaboodien, Gasnat, Da Silva, Rachael, Lee, Dave Chi Hoo, Frain, Simon, Geifman, Nophar, Whetton, Anthony D., Keavney, Bernard, Engel, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939134/
https://www.ncbi.nlm.nih.gov/pubmed/35317720
http://dx.doi.org/10.1186/s12014-022-09345-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939134/
https://www.ncbi.nlm.nih.gov/pubmed/35317720
http://dx.doi.org/10.1186/s12014-022-09345-1

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